載入...

Destabilization of tetraplex structures of the fragile X repeat sequence (CGG)(n) is mediated by homolog-conserved domains in three members of the hnRNP family

Hairpin or tetrahelical structures formed by a d(CGG)(n) sequence in the FMR1 gene are thought to promote expansion of the repeat tract. Subsequent to this expansion FMR1 is silenced and fragile X syndrome ensues. The injurious effects of d(CGG)(n) secondary structures may potentially be countered b...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Khateb, Samer, Weisman-Shomer, Pnina, Hershco, Inbal, Loeb, Lawrence A., Fry, Michael
格式: Artigo
語言:Inglês
出版: Oxford University Press 2004
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15302914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh745
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!