STAT3 modulates β-cell cycling in injured mouse pancreas and protects against DNA damage

Partial pancreatic duct ligation (PDL) of mouse pancreas induces a doubling of the β-cell mass mainly through proliferation of pre-existing and newly formed β-cells. The molecular mechanism governing this process is still largely unknown. Given the inflammatory nature of PDL and inflammation-induced...

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Опубликовано в: :Cell Death Dis
Главные авторы: De Groef, S, Renmans, D, Cai, Y, Leuckx, G, Roels, S, Staels, W, Gradwohl, G, Baeyens, L, Heremans, Y, Martens, G A, De Leu, N, Sojoodi, M, Van de Casteele, M, Heimberg, H
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143397/
https://ncbi.nlm.nih.gov/pubmed/27336716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.171
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