CD36 Provides Host Protection Against Klebsiella pneumoniae Intrapulmonary Infection by Enhancing Lipopolysaccharide Responsiveness and Macrophage Phagocytosis

Klebsiella pneumoniae remains an important cause of intrapulmonary infection and invasive disease worldwide. K. pneumoniae can evade serum killing and phagocytosis primarily through the expression of a polysaccharide capsule, but its pathogenicity is also influenced by host factors. We examined whet...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Olonisakin, Tolani F., Li, Huihua, Xiong, Zeyu, Kochman, Elizabeth J. K., Yu, Minting, Qu, Yanyan, Hulver, Mei, Kolls, Jay K., St. Croix, Claudette, Doi, Yohei, Nguyen, Minh-Hong, Shanks, Robert M. Q., Mallampalli, Rama K., Kagan, Valerian E., Ray, Anuradha, Silverstein, Roy L., Ray, Prabir, Lee, Janet S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142085/
https://ncbi.nlm.nih.gov/pubmed/27683817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw451
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