Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance

BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common hematological malignancy in western countries, characterized by a heterogeneous clinical course. Although genetic studies have identified chromosomal aberrations or specific mutations, epigenetic changes have been poorly characterized...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Van Damme, Michaël, Crompot, Emerence, Meuleman, Nathalie, Maerevoet, Marie, Mineur, Philippe, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141649/
https://ncbi.nlm.nih.gov/pubmed/27980696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0298-y
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