HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance

Histone deacetylases (HDACs) play a crucial role in chromatin structure and, consequently, gene expression. Their deregulation has been reported in various cancers. We performed a complete and comprehensive study of the expression of 18 HDACs (including Sirtuin; SIRT) by real-time PCR in a cohort of...

詳細記述

保存先:
書誌詳細
主要な著者: Van Damme, Michaël, Crompot, Emerence, Meuleman, Nathalie, Mineur, Philippe, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528695/
https://ncbi.nlm.nih.gov/pubmed/23108383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22674
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