Importance of Crosstalk Between Chronic Lymphocytic Leukemia Cells and the Stromal Microenvironment: Direct Contact, Soluble Factors, and Extracellular Vesicles

Chronic lymphocytic leukemia (CLL) is caused by the accumulation of malignant B cells due to a defect in apoptosis and the presence of small population of proliferating cells principally in the lymph nodes. The abnormal survival of CLL B cells is explained by a plethora of supportive stimuli produce...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Dubois, Nathan, Crompot, Emerence, Meuleman, Nathalie, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466743/
https://ncbi.nlm.nih.gov/pubmed/32974152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01422
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