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Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

Small heat shock proteins (sHsp) constitute an evolutionary conserved yet diverse family of chaperones acting as first line of defence against proteotoxic stress. sHsps coaggregate with misfolded proteins but the molecular basis and functional implications of these interactions, as well as potential...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Ungelenk, Sophia, Moayed, Fatemeh, Ho, Chi-Ting, Grousl, Tomas, Scharf, Annette, Mashaghi, Alireza, Tans, Sander, Mayer, Matthias P., Mogk, Axel, Bukau, Bernd
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141385/
https://ncbi.nlm.nih.gov/pubmed/27901028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13673
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