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Role of sHsps in organizing cytosolic protein aggregation and disaggregation

Small heat shock proteins (sHsps) exhibit an ATP-independent chaperone activity to prevent the aggregation of misfolded proteins in vitro. The seemingly conflicting presence of sHsps in insoluble protein aggregates in cells obstructs a precise definition of sHsp function in proteostasis networks. Re...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Mogk, Axel, Bukau, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465027/
https://ncbi.nlm.nih.gov/pubmed/28120291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0762-4
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