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Hsp42 is required for sequestration of protein aggregates into deposition sites in Saccharomyces cerevisiae

The aggregation of proteins inside cells is an organized process with cytoprotective function. In Saccharomyces cerevisiae, aggregating proteins are spatially sequestered to either juxtanuclear or peripheral sites, which target distinct quality control pathways for refolding and degradation. The cel...

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Detalhes bibliográficos
Main Authors: Specht, Sebastian, Miller, Stephanie B.M., Mogk, Axel, Bukau, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257523/
https://ncbi.nlm.nih.gov/pubmed/22065637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106037
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