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Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition
Disruption of the functional protein balance in living cells activates protective quality control systems to repair damaged proteins or sequester potentially cytotoxic misfolded proteins into aggregates. The established model based on Saccharomyces cerevisiae indicates that aggregating proteins in t...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369314/ https://ncbi.nlm.nih.gov/pubmed/25672362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489524 |
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