C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Among various innate immune receptor families, the role of C-type lectin receptors (CLRs) in lung protective immunity against Streptococcus pneumoniae (S. pneumoniae) is not fully defined. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar...

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Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Behler-Janbeck, Friederike, Takano, Tomotsugu, Maus, Regina, Stolper, Jennifer, Jonigk, Danny, Tort Tarrés, Meritxell, Fuehner, Thomas, Prasse, Antje, Welte, Tobias, Timmer, Mattie S. M., Stocker, Bridget L., Nakanishi, Yoichi, Miyamoto, Tomofumi, Yamasaki, Sho, Maus, Ulrich A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140071/
https://ncbi.nlm.nih.gov/pubmed/27923071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006038
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