C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Among various innate immune receptor families, the role of C-type lectin receptors (CLRs) in lung protective immunity against Streptococcus pneumoniae (S. pneumoniae) is not fully defined. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar...

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發表在:PLoS Pathog
Main Authors: Behler-Janbeck, Friederike, Takano, Tomotsugu, Maus, Regina, Stolper, Jennifer, Jonigk, Danny, Tort Tarrés, Meritxell, Fuehner, Thomas, Prasse, Antje, Welte, Tobias, Timmer, Mattie S. M., Stocker, Bridget L., Nakanishi, Yoichi, Miyamoto, Tomofumi, Yamasaki, Sho, Maus, Ulrich A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140071/
https://ncbi.nlm.nih.gov/pubmed/27923071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006038
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