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Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses

C-type lectin receptors (CLRs) are an emerging family of pattern recognition receptors that recognizes pathogens or damaged tissue to trigger innate immune responses. However, endogenous ligands for CLRs are not fully understood. In this study, we sought to identify an endogenous ligand(s) for human...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kiyotake, Ryoko, Oh-hora, Masatsugu, Ishikawa, Eri, Miyamoto, Tomofumi, Ishibashi, Tatsuro, Yamasaki, Sho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646182/
https://ncbi.nlm.nih.gov/pubmed/26296894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645234
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