Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses

C-type lectin receptors (CLRs) are an emerging family of pattern recognition receptors that recognizes pathogens or damaged tissue to trigger innate immune responses. However, endogenous ligands for CLRs are not fully understood. In this study, we sought to identify an endogenous ligand(s) for human...

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Опубликовано в: :J Biol Chem
Главные авторы: Kiyotake, Ryoko, Oh-hora, Masatsugu, Ishikawa, Eri, Miyamoto, Tomofumi, Ishibashi, Tatsuro, Yamasaki, Sho
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646182/
https://ncbi.nlm.nih.gov/pubmed/26296894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645234
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