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Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses
C-type lectin receptors (CLRs) are an emerging family of pattern recognition receptors that recognizes pathogens or damaged tissue to trigger innate immune responses. However, endogenous ligands for CLRs are not fully understood. In this study, we sought to identify an endogenous ligand(s) for human...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646182/ https://ncbi.nlm.nih.gov/pubmed/26296894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645234 |
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