CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment

Tumor cells and tumor-infiltrating macrophages produce the chemokine CCL22, which attracts regulatory T cells (Tregs) into the tumor microenvironment, decreasing anticancer immunity. Here, we investigated the possibility of targeting CCL22-expressing cells by activating specific T cells. We analyzed...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Martinenaite, Evelina, Munir Ahmad, Shamaila, Hansen, Morten, Met, Özcan, Westergaard, Marie Wulff, Larsen, Stine Kiaer, Klausen, Tobias Wirenfeldt, Donia, Marco, Svane, Inge Marie, Andersen, Mads Hald
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139648/
https://ncbi.nlm.nih.gov/pubmed/27999757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1238541
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