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Frequent adaptive immune responses against arginase-1
The enzyme arginase-1 reduces the availability of arginine to tumor-infiltrating immune cells, thus reducing T-cell functionality in the tumor milieu. Arginase-1 is expressed by some cancer cells and by immune inhibitory cells, such as myeloid-derived suppressor cells (MDSCs) and tumor-associated ma...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790367/ https://ncbi.nlm.nih.gov/pubmed/29399404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1404215 |
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