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Spontaneous presence of FOXO3-specific T cells in cancer patients

In the present study, we describe forkhead box O3 (FOXO3)-specific, cytotoxic CD8(+) T cells existent among peripheral-blood mononuclear cells (PBMCs) of cancer patients. FOXO3 immunogenicity appears specific, as we did not detect reactivity toward FOXO3 among T cells in healthy individuals. FOXO3 m...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Larsen, Stine Kiaer, Ahmad, Shamaila Munir, Idorn, Manja, Met, Özcan, Martinenaite, Evelina, Svane, Inge Marie, Straten, Per thor, Andersen, Mads Hald
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368145/
https://ncbi.nlm.nih.gov/pubmed/25960934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.953411
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