Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer

Tryptophan-2,3-dioxygenase (TDO) physiologically regulates systemic tryptophan levels in the liver. However, numerous studies have linked cancer with activation of local and systemic tryptophan metabolism. Indeed, similar to other heme dioxygenases TDO is constitutively expressed in many cancers. In...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Hjortsø, Mads Duus, Larsen, Stine Kiaer, Kongsted, Per, Met, Özcan, Frøsig, Thomas Mørch, Andersen, Gitte Holmen, Ahmad, Shamaila Munir, Svane, Inge Marie, Becker, Jürgen C, Straten, Per thor, Andersen, Mads Hald
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368150/
https://ncbi.nlm.nih.gov/pubmed/25949861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.968480
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