Natural CD4(+) T-Cell Responses against Indoleamine 2,3-Dioxygenase

BACKGROUND: The enzyme indoleamine 2,3-dioxygenase (IDO) contributes to immune tolerance in a variety of settings. In cancer IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it endorses the establishment of peripheral immune toleran...

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Главные авторы: Munir, Shamaila, Larsen, Stine Kiaer, Iversen, Trine Zeeberg, Donia, Marco, Klausen, Tobias Wirenfeldt, Svane, Inge Marie, Straten, Per thor, Andersen, Mads Hald
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335144/
https://ncbi.nlm.nih.gov/pubmed/22539948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034568
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