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Natural CD4(+) T-Cell Responses against Indoleamine 2,3-Dioxygenase
BACKGROUND: The enzyme indoleamine 2,3-dioxygenase (IDO) contributes to immune tolerance in a variety of settings. In cancer IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it endorses the establishment of peripheral immune toleran...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335144/ https://ncbi.nlm.nih.gov/pubmed/22539948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034568 |
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