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Design and mechanistic insight into ultrafast calcium indicators for monitoring intracellular calcium dynamics
Calmodulin-based genetically encoded fluorescent calcium indicators (GCaMP-s) are powerful tools of imaging calcium dynamics from cells to freely moving animals. High affinity indicators with slow kinetics however distort the temporal profile of calcium transients. Here we report the development of...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5138832/ https://ncbi.nlm.nih.gov/pubmed/27922063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38276 |
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