Single Synapse Indicators of Impaired Glutamate Clearance Derived from Fast iGlu(u) Imaging of Cortical Afferents in the Striatum of Normal and Huntington (Q175) Mice

Changes in the balance between glutamate (Glu) release and uptake may stimulate synaptic reorganization and even synapse loss. In the case of neurodegeneration, a mismatch between astroglial Glu uptake and presynaptic Glu release could be detected if both parameters were assessed independently and a...

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Publicat a:J Neurosci
Autors principals: Dvorzhak, Anton, Helassa, Nordine, Török, Katalin, Schmitz, Dietmar, Grantyn, Rosemarie
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520508/
https://ncbi.nlm.nih.gov/pubmed/30819797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2865-18.2019
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