Single Synapse Indicators of Impaired Glutamate Clearance Derived from Fast iGlu(u) Imaging of Cortical Afferents in the Striatum of Normal and Huntington (Q175) Mice

Changes in the balance between glutamate (Glu) release and uptake may stimulate synaptic reorganization and even synapse loss. In the case of neurodegeneration, a mismatch between astroglial Glu uptake and presynaptic Glu release could be detected if both parameters were assessed independently and a...

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Pubblicato in:J Neurosci
Autori principali: Dvorzhak, Anton, Helassa, Nordine, Török, Katalin, Schmitz, Dietmar, Grantyn, Rosemarie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520508/
https://ncbi.nlm.nih.gov/pubmed/30819797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2865-18.2019
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