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Design and mechanistic insight into ultrafast calcium indicators for monitoring intracellular calcium dynamics

Calmodulin-based genetically encoded fluorescent calcium indicators (GCaMP-s) are powerful tools of imaging calcium dynamics from cells to freely moving animals. High affinity indicators with slow kinetics however distort the temporal profile of calcium transients. Here we report the development of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Helassa, Nordine, Podor, Borbala, Fine, Alan, Török, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138832/
https://ncbi.nlm.nih.gov/pubmed/27922063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38276
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