Fast-Response Calmodulin-Based Fluorescent Indicators Reveal Rapid Intracellular Calcium Dynamics

Faithful reporting of temporal patterns of intracellular Ca(2+) dynamics requires the working range of indicators to match the signals. Current genetically encoded calmodulin-based fluorescent indicators are likely to distort fast Ca(2+) signals by apparent saturation and integration due to their li...

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Udgivet i:Sci Rep
Main Authors: Helassa, Nordine, Zhang, Xiao-hua, Conte, Ianina, Scaringi, John, Esposito, Elric, Bradley, Jonathan, Carter, Thomas, Ogden, David, Morad, Martin, Török, Katalin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630588/
https://ncbi.nlm.nih.gov/pubmed/26527405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15978
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