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The kinetic mechanisms of fast-decay red-fluorescent genetically encoded calcium indicators

Genetically encoded calcium indicators (GECIs) are useful reporters of cell-signaling, neuronal, and network activities. We have generated novel fast variants and investigated the kinetic mechanisms of two recently developed red-fluorescent GECIs (RGECIs), mApple-based jRGECO1a and mRuby-based jRCaM...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Kerruth, Silke, Coates, Catherine, Dürst, Céline D., Oertner, Thomas G., Török, Katalin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422079/
https://ncbi.nlm.nih.gov/pubmed/30651353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004543
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