Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

Non-alcoholic steatohepatitis (NASH) is characterized by liver lipid accumulation and inflammation. The mechanisms that trigger hepatic inflammation are poorly understood and subsequently, no specific non-invasive markers exist. We previously demonstrated a reduction in the plasma lysosomal enzyme,...

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Опубликовано в: :Sci Rep
Главные авторы: Walenbergh, Sofie M. A., Houben, Tom, Rensen, Sander S., Bieghs, Veerle, Hendrikx, Tim, van Gorp, Patrick J., Oligschlaeger, Yvonne, Jeurissen, Mike L. J., Gijbels, Marion J. J., Buurman, Wim A., Vreugdenhil, Anita C. E., Greve, Jan Willem M., Plat, Jogchum, Hofker, Marten H., Kalhan, Satish, Pihlajamäki, Jussi, Lindsey, Patrick, Koek, Ger H., Shiri-Sverdlov, Ronit
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138820/
https://ncbi.nlm.nih.gov/pubmed/27922112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38278
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