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Cathepsin D regulates lipid metabolism in murine steatohepatitis

Due to the obesity epidemic, non-alcoholic steatohepatitis (NASH) is a prevalent liver disease, characterized by fat accumulation and inflammation of the liver. However, due to a lack of mechanistic insight, diagnostic and therapeutic options for NASH are poor. Recent evidence has indicated cathepsi...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Houben, Tom, Oligschlaeger, Yvonne, Hendrikx, Tim, Bitorina, Albert V., Walenbergh, Sofie M. A., van Gorp, Patrick J., Gijbels, Marion J. J., Friedrichs, Silvia, Plat, Jogchum, Schaap, Frank G., Lütjohann, Dieter, Hofker, Marten H., Shiri-Sverdlov, Ronit
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471235/
https://ncbi.nlm.nih.gov/pubmed/28615690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03796-5
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