Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

Non-alcoholic steatohepatitis (NASH) is characterized by liver lipid accumulation and inflammation. The mechanisms that trigger hepatic inflammation are poorly understood and subsequently, no specific non-invasive markers exist. We previously demonstrated a reduction in the plasma lysosomal enzyme,...

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Publicado no:Sci Rep
Main Authors: Walenbergh, Sofie M. A., Houben, Tom, Rensen, Sander S., Bieghs, Veerle, Hendrikx, Tim, van Gorp, Patrick J., Oligschlaeger, Yvonne, Jeurissen, Mike L. J., Gijbels, Marion J. J., Buurman, Wim A., Vreugdenhil, Anita C. E., Greve, Jan Willem M., Plat, Jogchum, Hofker, Marten H., Kalhan, Satish, Pihlajamäki, Jussi, Lindsey, Patrick, Koek, Ger H., Shiri-Sverdlov, Ronit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138820/
https://ncbi.nlm.nih.gov/pubmed/27922112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38278
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