Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

Non-alcoholic steatohepatitis (NASH) is characterized by liver lipid accumulation and inflammation. The mechanisms that trigger hepatic inflammation are poorly understood and subsequently, no specific non-invasive markers exist. We previously demonstrated a reduction in the plasma lysosomal enzyme,...

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Publicat a:Sci Rep
Autors principals: Walenbergh, Sofie M. A., Houben, Tom, Rensen, Sander S., Bieghs, Veerle, Hendrikx, Tim, van Gorp, Patrick J., Oligschlaeger, Yvonne, Jeurissen, Mike L. J., Gijbels, Marion J. J., Buurman, Wim A., Vreugdenhil, Anita C. E., Greve, Jan Willem M., Plat, Jogchum, Hofker, Marten H., Kalhan, Satish, Pihlajamäki, Jussi, Lindsey, Patrick, Koek, Ger H., Shiri-Sverdlov, Ronit
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138820/
https://ncbi.nlm.nih.gov/pubmed/27922112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38278
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