CD98-mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is an aggressive disease associated with drug resistance and relapse. To improve therapeutic strategies, it is critical to better understand the mechanisms that underlie AML progression. Here we show that the integrin binding glycoprotein CD98 plays a central role in...

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Bibliografiset tiedot
Julkaisussa:Cancer Cell
Päätekijät: Bajaj, Jeevisha, Konuma, Takaaki, Lytle, Nikki K., Kwon, Hyog Young, Ablack, Jailal N., Cantor, Joseph M., Rizzieri, David, Chuah, Charles, Oehler, Vivian G., Broome, Elizabeth H., Ball, Edward D., van der Horst, Edward H., Ginsberg, Mark H., Reya, Tannishtha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137811/
https://ncbi.nlm.nih.gov/pubmed/27908736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.10.003
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