CD98-mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia

Acute myelogenous leukemia (AML) is an aggressive disease associated with drug resistance and relapse. To improve therapeutic strategies, it is critical to better understand the mechanisms that underlie AML progression. Here we show that the integrin binding glycoprotein CD98 plays a central role in...

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Publicado en:Cancer Cell
Autores principales: Bajaj, Jeevisha, Konuma, Takaaki, Lytle, Nikki K., Kwon, Hyog Young, Ablack, Jailal N., Cantor, Joseph M., Rizzieri, David, Chuah, Charles, Oehler, Vivian G., Broome, Elizabeth H., Ball, Edward D., van der Horst, Edward H., Ginsberg, Mark H., Reya, Tannishtha
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137811/
https://ncbi.nlm.nih.gov/pubmed/27908736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.10.003
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