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Dephosphorylation of the Retinoblastoma protein (Rb) inhibits cancer cell EMT via Zeb
The tumor suppressor Retinoblastoma (Rb) protein is highly phosphorylated in cancer cells largely due to the overexpression of cyclins or the loss of expression of cyclin dependent kinase inhibitors (cdki). Hyperphosphorylation of Rb promotes proliferation, and plays a role in the regulation of apop...
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| Publicado no: | Cancer Biol Ther |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137485/ https://ncbi.nlm.nih.gov/pubmed/27645778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1235668 |
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