Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance

Telomeres are specialized nucleoprotein complexes that comprise the ends of linear chromosomes. Human telomeres end in a short, single-stranded DNA (ssDNA) overhang that is recognized and bound by two telomere proteins, POT1 and TPP1. Whereas POT1 binds directly to telomere ssDNA, its interaction wi...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Rajavel, Malligarjunan, Orban, Tivadar, Xu, Mengyuan, Hernandez-Sanchez, Wilnelly, de la Fuente, Maria, Palczewski, Krzysztof, Taylor, Derek J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137443/
https://ncbi.nlm.nih.gov/pubmed/27655633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw846
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