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POT1-TPP1 binding and unfolding of telomere DNA discriminates against structural polymorphism
Telomeres are nucleoprotein complexes that reside at the ends of linear chromosomes and help maintain genomic integrity. POT1 and TPP1 are telomere-specific proteins that bind as a heterodimer to single-stranded telomere DNA to prevent illicit DNA damage responses and to enhance telomerase-mediated...
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| Publicado no: | J Mol Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905795/ https://ncbi.nlm.nih.gov/pubmed/27173378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.04.031 |
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