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Molecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporter

ATP-binding cassette (ABC) transporters use ATP to translocate various substrates across cellular membranes. Several members of subfamily A of mammalian ABC transporters are associated with severe health disorders, but their unusual complexity and large size have so far precluded structural characte...

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Autori principali: Tsybovsky, Yaroslav, Orban, Tivadar, Molday, Robert S., Taylor, Derek, Palczewski, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654078/
https://ncbi.nlm.nih.gov/pubmed/23562398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.03.001
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