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Structural insights into the activation of human relaxin family peptide receptor 1 by small molecule agonists
The GPCR relaxin family peptide receptor 1 (RXFP1) mediates the action of relaxin peptide hormone including its tissue remodeling and antifibrotic effects. The peptide hormone has a short half-life in plasma, limiting its therapeutic utility. However, small molecule agonists of human RXFP1 can overc...
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| 出版年: | Biochemistry |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137375/ https://ncbi.nlm.nih.gov/pubmed/26866459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01195 |
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