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DNA intercalation optimized by two-step molecular lock mechanism

The diverse properties of DNA intercalators, varying in affinity and kinetics over several orders of magnitude, provide a wide range of applications for DNA-ligand assemblies. Unconventional intercalation mechanisms may exhibit high affinity and slow kinetics, properties desired for potential therap...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Almaqwashi, Ali A., Andersson, Johanna, Lincoln, Per, Rouzina, Ioulia, Westerlund, Fredrik, Williams, Mark C.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137138/
https://ncbi.nlm.nih.gov/pubmed/27917863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37993
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