Dissecting the Dynamic Pathways of Stereoselective DNA Threading Intercalation

DNA intercalators that have high affinity and slow kinetics are developed for potential DNA-targeted therapeutics. Although many natural intercalators contain multiple chiral subunits, only intercalators with a single chiral unit have been quantitatively probed. Dumbbell-shaped DNA threading interca...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Almaqwashi, Ali A., Andersson, Johanna, Lincoln, Per, Rouzina, Ioulia, Westerlund, Fredrik, Williams, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Nucleic Acids and Genome Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816715/
https://ncbi.nlm.nih.gov/pubmed/27028636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.02.016
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