Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling

The interaction dynamics of signaling complexes is emerging as a key determinant that regulates the specificity of cellular responses. We present a combined experimental and computational study that quantifies the consequences of plasma membrane microcompartmentalization for the dynamics of type I i...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: You, Changjiang, Marquez-Lago, Tatiana T., Richter, Christian Paolo, Wilmes, Stephan, Moraga, Ignacio, Garcia, K. Christopher, Leier, André, Piehler, Jacob
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135388/
https://ncbi.nlm.nih.gov/pubmed/27957535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600452
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