Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma

Janus kinases (JAKs) classically signal by activating STAT transcription factors but can also regulate gene expression by epigenetically phosphorylating histone H3 on tyrosine 41 (H3Y41-P). In diffuse large B-cell lymphomas (DLBCLs), JAK signaling is a feature of the activated B-cell (ABC) subtype a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rui, Lixin, Drennan, Amanda C., Ceribelli, Michele, Zhu, Fen, Wright, George W., Huang, Da Wei, Xiao, Wenming, Li, Yangguang, Grindle, Kreg M., Lu, Li, Hodson, Daniel J., Shaffer, Arthur L., Zhao, Hong, Xu, Weihong, Yang, Yandan, Staudt, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135360/
https://ncbi.nlm.nih.gov/pubmed/27799566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610970113
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