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Janus Kinase Deregulation in Leukemia and Lymphoma

Genetic alterations affecting members of the Janus kinase (JAK) family have been discovered in a wide array of cancers and are particularly prominent in hematological malignancies. In this review, we focus on the role of such lesions in both myeloid and lymphoid tumors. Oncogenic JAK molecules can a...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Chen, Edwin, Staudt, Louis M., Green, Anthony R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480953/
https://ncbi.nlm.nih.gov/pubmed/22520846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.017
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