RhoA/ROCK Signaling Regulates TGFβ-Induced Epithelial-Mesenchymal Transition of Lens Epithelial Cells through MRTF-A

Transforming growth factor (TGF)-β–induced epithelial-mesenchymal transition (EMT) leads to the formation of ocular fibrotic pathologies, such as anterior subcapsular cataract and posterior capsule opacification. Remodeling of the actin cytoskeleton, mediated by the Rho family of GTPases, plays a ke...

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Bibliografiska uppgifter
I publikationen:Mol Med
Huvudupphovsmän: Korol, Anna, Taiyab, Aftab, West-Mays, Judith A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Feinstein Institute for Medical Research 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135079/
https://ncbi.nlm.nih.gov/pubmed/27704140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00041
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