RhoA/ROCK Signaling Regulates TGFβ-Induced Epithelial-Mesenchymal Transition of Lens Epithelial Cells through MRTF-A

Transforming growth factor (TGF)-β–induced epithelial-mesenchymal transition (EMT) leads to the formation of ocular fibrotic pathologies, such as anterior subcapsular cataract and posterior capsule opacification. Remodeling of the actin cytoskeleton, mediated by the Rho family of GTPases, plays a ke...

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發表在:Mol Med
Main Authors: Korol, Anna, Taiyab, Aftab, West-Mays, Judith A
格式: Artigo
語言:Inglês
出版: Feinstein Institute for Medical Research 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135079/
https://ncbi.nlm.nih.gov/pubmed/27704140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00041
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