Lens Fibrosis: Understanding the Dynamics of Cell Adhesion Signaling in Lens Epithelial-Mesenchymal Transition

Injury to the ocular lens perturbs cell-cell and cell-capsule/basement membrane interactions leading to a myriad of interconnected signaling events. These events include cell-adhesion and growth factor-mediated signaling pathways that can ultimately result in the induction and progression of epithel...

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Main Authors: Aftab Taiyab, Judith West-Mays
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cell and Developmental Biology
Assuntos:
ocular lens
transforming growth factor β
epithelial to mesenchymal transition
fibrosis
cell adhesion
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcell.2022.886053/full
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