RhoA/ROCK Signaling Regulates TGFβ-Induced Epithelial-Mesenchymal Transition of Lens Epithelial Cells through MRTF-A

Transforming growth factor (TGF)-β–induced epithelial-mesenchymal transition (EMT) leads to the formation of ocular fibrotic pathologies, such as anterior subcapsular cataract and posterior capsule opacification. Remodeling of the actin cytoskeleton, mediated by the Rho family of GTPases, plays a ke...

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Pubblicato in:Mol Med
Autori principali: Korol, Anna, Taiyab, Aftab, West-Mays, Judith A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Feinstein Institute for Medical Research 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135079/
https://ncbi.nlm.nih.gov/pubmed/27704140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00041
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