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Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract

The most common vision-disrupting complication of cataract surgery is posterior capsule opacification (PCO; secondary cataract). PCO is caused by residual lens cells undergoing one of two very different cell fates: either transdifferentiating into myofibroblasts or maturing into lens fiber cells. Al...

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Pubblicato in:Mol Biol Cell
Autori principali: Boswell, Bruce A., Korol, Anna, West-Mays, Judith A., Musil, Linda S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385940/
https://ncbi.nlm.nih.gov/pubmed/28209733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0865
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