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Essential Role of BMPs in FGF-Induced Secondary Lens Fiber Differentiation

It is widely accepted that vitreous humor-derived FGFs are required for the differentiation of anterior lens epithelial cells into crystallin-rich fibers. We show that BMP 2, 4, and 7 can induce the expression of markers of fiber differentiation in primary lens cell cultures to an extent equivalent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Boswell, Bruce A, Overbeek, Paul A, Musil, Linda S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853743/
https://ncbi.nlm.nih.gov/pubmed/18848538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.09.003
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