In vivo visualization of tau deposits in corticobasal syndrome by (18)F-THK5351 PET

OBJECTIVE: To determine whether (18)F-THK5351 PET can be used to visualize tau deposits in brain lesions in live patients with corticobasal syndrome (CBS). METHODS: We evaluated the in vitro binding of (3)H-THK5351 in postmortem brain tissues from a patient with corticobasal degeneration (CBD). In c...

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Publicat a:Neurology
Autors principals: Kikuchi, Akio, Okamura, Nobuyuki, Hasegawa, Takafumi, Harada, Ryuichi, Watanuki, Shoichi, Funaki, Yoshihito, Hiraoka, Kotaro, Baba, Toru, Sugeno, Naoto, Oshima, Ryuji, Yoshida, Shun, Kobayashi, Junpei, Ezura, Michinori, Kobayashi, Michiko, Tano, Ohito, Mugikura, Shunji, Iwata, Ren, Ishiki, Aiko, Furukawa, Katsutoshi, Arai, Hiroyuki, Furumoto, Shozo, Tashiro, Manabu, Yanai, Kazuhiko, Kudo, Yukitsuka, Takeda, Atsushi, Aoki, Masashi
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135024/
https://ncbi.nlm.nih.gov/pubmed/27794115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003375
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