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Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation
Ewing sarcoma (ES) is the second most frequent childhood bone cancer driven by the EWS/FLI1 (EF) fusion protein. Genetically defined ES models are needed to understand how EF expression changes bone precursor cell differentiation, how ES arises and through which mechanisms of inhibition it can be ta...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5133963/ https://ncbi.nlm.nih.gov/pubmed/27735950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.268 |
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