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Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation
Feglymycin is a naturally occurring, anti-HIV and antimicrobial 13-mer peptide that includes highly racemizable 3,5-dihydroxyphenylglycines (Dpgs). Here we describe the total synthesis of feglymycin based on a linear/convergent hybrid approach. Our originally developed micro-flow amide bond formatio...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5133696/ https://ncbi.nlm.nih.gov/pubmed/27892469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13491 |
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