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Efficient Amide Bond Formation through a Rapid and Strong Activation of Carboxylic Acids in a Microflow Reactor**
The development of highly efficient amide bond forming methods which are devoid of side reactions, including epimerization, is important, and such a method is described herein and is based on the concept of rapid and strong activation of carboxylic acids. Various carboxylic acids are rapidly (0.5 s)...
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Publicado no: | Angew Chem Int Ed Engl |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
WILEY-VCH Verlag
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499250/ https://ncbi.nlm.nih.gov/pubmed/24402801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307987 |
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