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Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals
BACKGROUND: Advances in whole genome sequencing have enabled the investigation of rare variants, which could explain some of the missing heritability that genome-wide association studies are unable to detect. Most methods to detect associations with rare variants are developed for unrelated individu...
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| Veröffentlicht in: | BMC Proc |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5133523/ https://ncbi.nlm.nih.gov/pubmed/27980637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0031-z |
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